Your Cells Have Weird 'Tentacles' That Help Them Move Around. Here's How They Work
A cell is not an island. Each one has a host of ways to detect its surroundings, and even physically reach out to neighbors or enemies using strange cellular appendages. These tentacle-like protrusions are called filopodia , and a new study has given us more insight into how they allow our cells to move about, by twisting the skeleton-like inner scaffolding. "These structures play a pivotal role in .. allowing cells to explore their environment, generate mechanical forces, perform chemical signaling, or convey signals via intercellular tunneling nano-bridges," the researchers write in their paper . "The dynamics of filopodia appear quite complex as they exhibit a rich behavior of buckling, pulling, length and shape changes. Here, we show that filopodia additionally explore their 3D extracellular space by combining growth and shrinking with axial twisting and buckling of their actin rich core." Said core is composed of proteins called actin and myosin. The team, led ...